Cytokeratin-7 Mouse monoclonal Antibody IgG1

SKU: BA110222-100µl
$279.00Price

Fig1: Western blot analysis of Cytokeratin-7 on different cell lysates using anti- Cytokeratin-7 antibody at 1/1000 dilution.

Positive control:   

 Lane 1: MCF-7       

 Lane 2: A549 

 Lane 3: Hela         

 Lane 4: HepG2  

 Lane 5: SKBR3       Lane 6: SKOV3 

 Lane 7: SW1990

Fig2: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using anti-Cytokeratin-7 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-Cytokeratin-7 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA110222
Size
  • Host Species; Species Reactivity

    Mouse; Human
  • Immunogen

    Peptide
  • Application Summary

    WB, IHC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    KeRatin, type II cytoskeletal 7,KeRatin-7,Sarcolectin,Type-II keRatin Kb7
  • Background

    Keratin-7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Keratin-7 is found in simple glandular epithelia, and in transitional epithelium. Epithelial cells of the lung and breast both contain keratin-7, but some other glandular epithelia, such as those of the colon and prostate, do not. Because the keratin-7 antigen is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively.(EM0702)

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