CTNNBL1 Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis of CTNNBL1 on human CTNNBL1 recombinant protein using anti-CTNNBL1 antibody at 1/1,000 dilution.
Fig2: Western blot analysis of CTNNBL1 on HEK293 (1) and CTNNBL1-hIgGFc transfected HEK293 (2) cell lysate using anti-CTNNBL1 antibody at 1/1,000 dilution.
Fig3: Western blot analysis of CTNNBL1 on different cell lysate using anti-CTNNBL1 antibody at 1/1,000 dilution.
Positive control: Line1: Hela Line2: Jurkat Line3: HEK293 Line4: A431 Line5: HepG2 Line6: Raji
Host Species; Species ReactivityMouse; Human
Application SummaryWB, ICC, IHC, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesKeRatin, type II cytoskeletal 5, 58 kDa cytokeRatin, CytokeRatin-5, KeRatin-5, Type-II keRatin Kb5
BackgroundCTNNBL1 (catenin, β like 1), also known as NAP (nuclear-associated protein) or P14L, is an evolutionarily conserved protein with structural homology to members of the armadillo family, including β-catenin. CTNNBL1 is expressed in a variety of tissues with highest expression levels found in heart, spleen, testis, placenta, thyroid and skeletal muscle. Localizing to the nucleus, CTNNBL1 contains a bipartite nuclear localization signal, an acidic domain, a leucine-isoleucine zipper, an acidic domain and phosphorylation sites. Via its C-terminus, CTNNBL1 is believed to play a role in apoptosis. In addition, multiple SNPs (single nucleotide polymorphisms) in the CTNNBL1 have been associated with fat mass and body mass index (BMI), suggesting a possible role for CTNNBL1 in the development of obesity.(EM1706-34)