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CTDSPL Rabbit polyclonal Antibody IgG

SKU: BA111216-100µl
$279.00Price

Fig1: Western blot analysis of CTDSPL on HepG2 cell lysate using anti-CTDSPL antibody at 1/500 dilution.

Fig2: Flow cytometric analysis of HepG2 cells with CFTR antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

 

Bon Opus Cat. #BA111216
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein within human CTDSPL aa 50-300.
  • Application Summary

    WB,FC
  • Purification; Formulation

    Protein affinity purified. ; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    CTD small phosphatase-like protein, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, NIF-like protein, Nuclear LIM interactor-interacting factor 1, Protein YA22, RBSP3, Small C-terminal domain phosphatase 3
  • Background

    Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.(ER1803-59)