CSNK2B Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis of CSNK2B on human CSNK2B recombinant protein using anti-CSNK2B antibody at 1/1,000 dilution.
Fig2: Western blot analysis of CSNK2B on HEK293 (1) and CSNK2B-hIgGFc transfected HEK293 (2) cell lysate using anti-CSNK2B antibody at 1/1,000 dilution.
Fig3: Western blot analysis of CSNK2B on different cell lysates using anti-CSNK2B antibody at 1/1,000 dilution.
Positive control: Line1: Hela Line2: Jurkat Line3: K562 Line4: HepG2 Line5: C6 Line6: SK-N-SH Line7: NTERA-2 Line8: MCF-7 Line9: NIH/3T3
Host Species; Species ReactivityMouse; Human
Application SummaryWB, ICC, IHC, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesSomatostatin receptor type 3, SSR-28
BackgroundCasein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Ie, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.(EM1706-37)