CREB1 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on A431 (1) and PC12 (2) cell lysates using anti-CREB1 rabbit polyclonal antibodies.
Fig2: Immunofluorescent staining of Hela cells using anti- CREB1 rabbit polyclonal antibody.
Fig3: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti- CREB1 rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, ICC, IHC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesCyclic AMP-responsive element-binding protein 1
BackgroundCAMP responsive element binding protein 1, also known as CREB-1, is a protein that in humans is encoded by the CREB1 gene.This protein binds the cAMP response element, a DNA nucleotide sequence present in many viral and cellular promoters. The binding of CREB1 stimulates transcription.This protein is a CREB transcription factor that is a member of the leucine zipper family of DNA-binding proteins.CREB1 is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.(R1309-14)