Complement C3 (β chain) Rabbit polyclonal Antibody IgG

Complement C3 (β chain) Rabbit polyclonal Antibody IgG

SKU: BA110190-100µl
$279.00Price

Fig1: Western blot analysis on human serum using anti-complement C3 polyclonal antibody.  Note: 50kD band is caused by nonspecific reaction (goat anti-rabbit to human heavy chain).

 

 

Bon Opus Cat. #BA110190
Size
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

    Peptide
  • Application Summary

    WB
  • Purification; Formulation

    Immunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Complement C3,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
  • Background

    Human Complement C3 (C3) is synthesized as a single-chain pro-molecule (185 kDa) that tsuffers several posttranslational modifications. Before being a mature protein, C3 is split into beta-chain (70 kDa) and alpha chain (115 kDa) and forms a rare internal thioester bond. C3 plays a central role in the activation of the complement system. It’s processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.(0809-8)

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