Chromogranin A Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of chromogranin A on PC12 cell lysates using anti-chromogranin A antibody at 1/2000 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded rat pancreas tissue using anti-chromogranin A antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-chromogranin A antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, IHC, FC
Purification; FormulationPeptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesChromogranin-A,AL26,p-Glu serpinin precursor
BackgroundChromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A might promote the generation of secretory granules. It is used as an indicator for pancreas and prostate cancer. It might play a role in early neoplasic progression. It is also elevated in diabetes.(ER40724)