CD8 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on mouse Thymus using anti-CD8 polyclonal antibody
Host Species; Species ReactivityRabbit; Mouse
Application SummaryWB, ICC, IHC, FC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesT-cell surface glycoprotein CD8 alpha chain,T-cell surface glycoprotein Lyt-2,CD_antigen: CD8a
BackgroundThe CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain, a polypeptide linker, a transmembrane part and a short cytoplasmic tail. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. CD8 is thought to play a role in the process of T-cell mediated killing.(0108-7)