CD36 Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of CD36 on human heart (1) and mouse heart (2) tissue lysates using anti-CD36 antibody at 1/1,000 dilution.
Fig2: ICC staining CD36 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD36 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, ICC/IF, IHC, IP, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesPlatelet glycoprotein 4, Fatty acid translocase, Glycoprotein IIIb, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet collagen receptor, Platelet glycoprotein IV, Thrombospondin receptor, CD_antigen: CD36
BackgroundCD36 (collagen type I receptor, thrombospondin receptor, FAT, GP4, GP3B, GPIV, PASIV, SCARB3) is a membrane glycoprotein on platelets, monocytes and umbilical vein endothelial cells. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. CD36 plays a key role in both phagocytosis and lipid recycling, for constant production of mature spermatozoa. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. Thrombospondins are widely distributed proteins that influence a variety of adhesive processes and CD36 may have important functions as a cell adhesion molecule.(ET1701-24)