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©2020 by Bon Opus Biosciences, LLC.

CD20 Recombinant Rabbit monoclonal Antibody IgG

SKU: BA111415-100µl
$279.00Price

Fig1: Western blot analysis of CD20 on Raji cell lysates using anti-CD20 antibody at 1/1,000 dilution.

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD20 antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD20 antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA111415
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Monkey
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC, IP
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD_antigen: CD20
  • Background

    CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors.(ET1605-33)