CD11b Mouse monoclonal Antibody IgG2b
Fig1: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11b antibody. Counter stained with hematoxylin.
Fig2: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11b antibody. Counter stained with hematoxylin.
Fig3: Flow cytometric analysis of Raji cells with CD11b antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti mouse IgG (FITC) was used as the secondary antibody.
Host Species; Species ReactivityMouse; Human
ImmunogenRecombinant protein within human CD11b 500-750 aa.
Application SummaryIHC, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesIntegrin alpha-M,CD11 antigen-like family member B,CR-3 alpha chain，Cell surface glycoprotein MAC-1 subunit alpha,Leukocyte adhesion receptor MO1，Neutrophil adherence receptor，CD_antigen: CD11b
BackgroundIntegrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.(M1211-6)