CBX2 Mouse monoclonal Antibody IgG1
Fig1: Western blot analysis of CBX2 on human CBX2 recombinant protein using anti-CBX2 antibody at 1/1,000 dilution.
Fig2: Western blot analysis of CBX2 on HEK293 (1) and CBX2-hIgGFc transfected HEK293 (2) cell lysate using anti-CBX2 antibody at 1/1,000 dilution.
Fig3: Western blot analysis of CBX2 on different cell lysate using anti-CBX2 antibody at 1/1,000 dilution.
Positive control: Line1: HUVEC Line2: HEK293 Line3: Hela Line4: NIH/3T3 Line5: A431
Host Species; Species ReactivityMouse; Human, Mouse
Application SummaryWB, ICC, IHC, FC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesMatrix metalloproteinase-14, MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase
BackgroundComponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.(EM1706-28)