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Cathepsin D Rabbit polyclonal Antibody IgG

SKU: BA110841-100µl
$279.00Price

Fig1: Western blot analysis of Cathepsin D on different cell lysates using anti-Cathepsin D antibody at 1/1,000 dilution.

 Positive control:

 Lane 1: PC-12     

   Lane 2: MCF-7 Lane 3: NIH-3T3      Lane 4: Jurkat

Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA110841
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, IHC, FC
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain
  • Background

    The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.(R1601-2)