Cathepsin B Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of Cathepsin B on different cells lysates using anti-Cathepsin B antibody at 1/500 dilution.
Lane 1: HepG2
Lane 2: Hela
Fig2: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human
Application SummaryWB, ICC/IF, IHC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesCathepsin B, APP secretase, Cathepsin B1, Cathepsin B light chain, Cathepsin B heavy chain
BackgroundThe cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.(ET1704-03)