CASK Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of CASK on different cell lysate using anti-CASK antibody at 1/500 dilution.
Lane 1: SiHa
Lane 2: A549
Fig2: ICC staining CASK in HT-29 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining CASK in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Host Species; Species ReactivityRabbit; Human, Rat
ImmunogenRecombinant protein within human CASK aa 300-500.
Purification; FormulationProtein affinity purified.; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesPeripheral plasma membrane protein CASK, Calcium/calmodulin-dependent serine protein kinase, Protein lin-2 homolog
BackgroundMultidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.(ER1803-62)