Carbonic Anhydrase I Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of Carbonic Anhydrase I on different lysates using anti-Carbonic Anhydrase I antibody at 1/1,000 dilution.
Lane 1: Human colon
Lane 2: Mouse spleen
Lane 3: Mouse colon
Fig2: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Carbonic Anhydrase I antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human small intestine tissue using anti-Carbonic Anhydrase I antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
ImmunogenRecombinant protein within human Carbonic Anhydrase I aa 1-200.
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesCarbonic anhydrase 1, Carbonate dehydratase I, Carbonic anhydrase B, Carbonic anhydrase I
BackgroundCarbonic anhydrases (CAs), also designated carbonate dehydratases or carbonate hydrolyases, form a large family of genes that encode zinc metalloenzymes of great physiologic importance. As catalysts of the reversible hydration of carbon dioxide, these enzymes participate in a variety of biologic processes, including respiration, acid-base balance, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. Genes in the α-carbonic anhydrase family encode either active carbonic anhydrase isozymes or "acatalytic" (devoid of CO2 hydration activity) carbonic anhydrase-related proteins. Human CA I (CA1) is encoded by the CA1 gene, which maps to a region on chromosome 8 that harbors a cluster of CA genes. CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences.(ET7108-77)