C10orf58 Mouse monoclonal Antibody IgG2a
Fig1: Western blot analysis of C10orf58 on recombinant protein using anti-C10orf58 antibody at 1/1000 dilution.
Fig2: Western blot analysis of C10orf58 on human skin tissue lysate using anti-C10orf58 antibody at 1/1000 dilution.
Fig3: ICC staining C10orf58 (green) in HUVEC cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Host Species; Species ReactivityMouse; Human
Application SummaryWB, ICC
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesRedox-regulatory protein FAM213A, Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes
BackgroundFAM213A, also known as PAMM (peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) or C10orf58, is a 229 amino acid cytoplasmic protein that belongs to the peroxiredoxin-like FAM213 family and FAM213A subfamily. FAM213A plays a role in redox regulation of the cell, acts as an antioxidant, and is induced by CSF1 in peripheral blood mononuclear cells (PBMCs). Existing as two alternatively spliced isoforms, the gene encoding FAM213A maps to human chromosome 10. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes.(M1012-4)