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BMPR1A Rabbit polyclonal Antibody IgG

SKU: BA110098-100µl
$279.00Price

Fig1: Western blot analysis on 293 cell lysates using anti-BMPR1A rabbit polyclonal antibody.

Fig2:  Immunocytochemical staining of Hela cells using anti-BMPR1A rabbit polyclonal antibody.

Fig3:  Immunocytochemical staining of HepG2 cells using anti-BMPR1A rabbit polyclonal antibody.

Bon Opus Cat. #BA110098
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Recombinant protein
  • Application Summary

    WB, ICC, IHC, FC
  • Purification; Formulation

    Peptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Bone morphogenetic protein receptor type-1A,Activin receptor-like kinase 3,Serine/threonine-protein kinase receptor R5,CD_antigen: CD292
  • Background

    Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.(R1510-1)