BMP2 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of BMP2 on different lysates using anti-BMP2 antibody at 1/1,000 dilution.
Lane 1: Rat kidney
Lane 2: Mouse kidney
Lane 3: Human kidney
Lane 4: Hela
Fig2: ICC staining BMP2 in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. DAPI was used to stain the cell nuclei (blue).
Fig3: ICC staining BMP2 in MCF-7 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. DAPI was used to stain the cell nuclei (blue).
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
ImmunogenSynthetic Peptide (KLH-coupled) within human BMP2 N terminal.
Application SummaryWB, ICC, IHC, FC
Purification; FormulationPeptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesBone morphogenetic protein 2,Bone morphogenetic protein 2A
BackgroundBMP-2 belongs to the TGF-β superfamily of proteins. BMP-2 plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is involved also in cardiac cell differentiation and epithelial to mesenchymal transition. Implantation of BMP-2 in a collagen sponge induces new bone formation and can be used for the treatment of bony defects, delayed union, and non-union.(ER80602)