BCL2L1 Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on A431 and K562 cell lysates using anti-BCL2L1rabbit polyclonal antibodies.
Fig2: Immunofluorescent staining of Hela cells using anti- BCL2L1 rabbit polyclonal antibody.
Fig3: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti- BCL2L1 rabbit polyclonal antibody.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Application SummaryWB, ICC, IHC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesBcl-2-like protein 1,Apoptosis regulator Bcl-X
BackgroundBcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis. Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2. It appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.(R1308-16)