BCL2 Mouse monoclonal Antibody IgG

SKU: BA111200-100µl

Fig1: Western blot analysis of BCL2 on THP-1 lysate using anti-BCL2 antibody at 1/500 dilution.

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-BCL2 antibody. Counter stained with hematoxylin.


Bon Opus Cat. #BA111200
  • Host Species; Species Reactivity

    Mouse; Human
  • Immunogen

    Synthetic Peptide within human BCL2 35-60 aa.
  • Application Summary

  • Purification; Formulation

    Peptide affinity purified.; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Apoptosis regulator Bcl-2
  • Background

    Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.(EM1701-82)

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