BAX Rabbit polyclonal Antibody IgG

SKU: BA110851-100µl
$279.00Price

Fig1: ICC staining BAX in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig2: ICC staining BAX in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-BAX antibody. Counter stained with hematoxylin.

Bon Opus Cat. #BA110851
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse
  • Immunogen

    Peptide-KLH
  • Application Summary

    ICC, IHC
  • Purification; Formulation

    Peptide affinity purified; 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Apoptosis regulator BAX, Bcl-2-like protein 4
  • Background

    Bax is a key component for cellular induced apoptosis through mitochondrial stress. It accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, BAX undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. It promotes activation of CASP3, and thereby apoptosis.(R1706-19)

(800) 943-6396

150 Essex St, Millburn, NJ 07041, USA

©2020 by Bon Opus Biosciences, LLC.