AXL Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis of AXL on different lysates using anti-AXL antibody at 1/100 dilution.
Lane 1: Mouse kidney tissue
Lane 2: CRC
Fig2: Western blot analysis of AXL on human AXL recombinant protein using anti-AXL antibody at 1/1,000 dilution.
Fig3: ICC staining AXL in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Host Species; Species ReactivityRabbit; Human, Mouse
ImmunogenRecombinant protein within human AXL 1-200 aa.
Application SummaryWB, ICC
Purification; FormulationPeptide affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesTyrosine-protein kinase receptor UFO,AXL oncogene
BackgroundThe UFO family of receptor tyrosine kinases is comprised of subfamily members Rse (also designated Tyro3, Sky, Brt, Dtk, Etk2 and Tif), Axl (also designated UFO or ARK) and Mer (also designated Nyk or Eyk). Rse is expressed Preferentially in the adult brain with lower expression in other tissues. Axl is found at highest levels in heart and skeletal muscle. Mer has been identified as a tyrosine kinase is involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate , Lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S, have been identified as ligands for the UFO family of receptors.(R1406-3)