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ATG4C Mouse monoclonal Antibody IgG1

SKU: BA112775-100µl
$279.00Price
Bon Opus Cat. #BA112775
Size
  • Host Species; Species Reactivity

    Mouse; Human
  • Immunogen

    Recombinant protein
  • Application Summary

    WB
  • Purification; Formulation

    ProA affinity purified; 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Neuronal acetylcholine receptor subunit alpha-4
  • Background

    Atg4C (ATG4 autophagy related 4 homolog C), also known as AUTL1 (AUT-like 1, cysteine endopeptidase), AUTL3 (AUT-like 3 cysteine endopeptidase), APG4-C, autophagin-3 or cysteine protease ATG4C, is a 458 amino acid tumor suppressor protein belonging to the peptidase C54 family. Encoded by a gene that maps to human chromosome 1p31.3, Atg4C is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish. Atg4C is highly expressed in skeletal muscle, heart, liver and testis, and localizes to cytoplasm. Functioning as a cysteine protease, which is necessary for autophagy, Atg4C cleaves the C-terminal region of either MAP1LC3, GABARAPL2 or GABARAP. Atg4C is also inhibited by N-ethylmaleimide.(EM1706-78)