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Amyloid Beta A4 Precursor (APP) Rabbit polyclonal Antibody IgG

SKU: BA110054-100µl
$279.00Price

Fig1: Western blot analysis on Hela using anti-APP polyclonal antibody

Fig2: ICC on D3.

 

Bon Opus Cat. #BA110054
Size
  • Host Species; Species Reactivity

    Rabbit; Human, Mouse, Rat
  • Immunogen

    Peptide
  • Application Summary

    WB
  • Purification; Formulation

    Immunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Amyloid beta A4 protein,ABPP,APPI,Alzheimer disease amyloid protein,Cerebral vascular amyloid peptide,PreA4,Protease nexin-II
  • Background

    Amyloid beta precursor protein (APP) is a 100-140 kDa transmembrane glycoprotein existing as several isoforms. The amino acid sequence of APP contains the amyloid domain (A-beta), which can be released by a two-step proteolytic cleavage. It is expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. APP acts as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is also involved in cell mobility and transcription regulation through protein-protein interactions.(1007-5)