alpha 1-antitrypsin Rabbit polyclonal Antibody IgG

alpha 1-antitrypsin Rabbit polyclonal Antibody IgG

SKU: BA110033-100µl

Fig1: Western blot analysis on human plasma using anti- Alpha 1-Antitrypsin antibody.



Bon Opus Cat. #BA110033
  • Host Species; Species Reactivity

    Rabbit; Human
  • Immunogen

  • Application Summary

  • Purification; Formulation

    Immunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
  • ALTnames

    Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1
  • Background

    Alpha 1-Antitrypsin is a inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. It Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Defects in SERPINA1 are the cause of alpha-1-antitrypsin deficiency (A1ATD). A disorder whose most common manifestation is emphysema, which becomes evident by the third to fourth decade. A less common manifestation of the deficiency is liver disease, which occurs in children and adults, and may result in cirrhosis and liver failure.(R1103-1)

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