Alkaline Phosphatase (PLAP-1/PLAP-like) Rabbit polyclonal Antibody IgG
Fig1: Western blot analysis on Hela using anti-ALP polyclonal antibody
Host Species; Species ReactivityRabbit; Human
Application SummaryWB, IHC, FC
Purification; FormulationImmunogen affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesAlkaline phosphatase, placental type,Alkaline phosphatase Regan isozyme,Placental alkaline phosphatase 2
BackgroundAlkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Placental ALP is highly polymorphic, there are at least three common alleles. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.(0806-4)