ALDH1L1 Recombinant Rabbit monoclonal Antibody IgG
Fig1: Western blot analysis of ALDH1L1 on mouse liver tissue lysates using anti-ALDH1L1 antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-ALDH1L1 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-ALDH1L1 antibody. Counter stained with hematoxylin.
Host Species; Species ReactivityRabbit; Human, Mouse, Rat
Purification; FormulationProA affinity purified; 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.; Liquid form.
ALTnamesCytosolic 10-formyltetrahydrofolate dehydrogenase, Aldehyde dehydrogenase family 1 member L1
Background10-formyltetrahydrofolate dehydrogenase is an enzyme that in humans is encoded by the ALDH1L1 gene. The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.(ET7106-64)