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BA010043
0.2 mL
$420.00
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Mouse mAb anti- human Macrophage/Monocyte Chemotactic Protein-3 (MCP-3), Tracer (HRP Labeled), Clone 113

Cat No.: 
BA010043
Collection: 
Sub Category: 
Immunogen: 
Recombinant human MCP-3 (M.W. 8.5kDa containing 76 amino acids residues)
Host Species: 
Mouse
Clonality: 
Clone: 
113
Isotype: 
IgG1,k
Species Reactivity: 
Human, other species not tested
ALTnames: 
MCP3, c-c motif chemokine 7, cc motif chemokine 7, monocyte chemoattractant protein 3, Nc28, CCL7, CMP3, SCYA6, SCYA7
Specificity: 
This antibody reacts with Human MCP-3
Purification: 
Protein G affinity purified
Formulation: 
0.01M PBS, pH 7.2, containing 50% glycerol
Application Summary: 
ELISA: In combination with capture antibody clone 542 (MO-C40088G), this HRP conjugated antibody can be used as tracer antibody for human MCP-3 detection in sandwich ELISA.
Storage: 
Store at -20°C
Antigen Protein: 
Human MCP-3
Description: 
Horseradish peroxidase (HRP) conjugated mouse monoclonal antibody to human macrophage/monocyte chemotactic protein-3 (MCP-3)
Cross Reactivity: 
Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1β, IL-8, MCAF, SAA and EGF.
Background: 
Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78% sequence homology with MCP-1 and 58% sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.
MO-C40088T