Purified recombinant human GM-CSF
Human, other species not tested
Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF, Molgramostin, Sargramostim, GMCSF
This antibody reacts with Human GM-CSF
Protein G affinity purified
0.01M PBS, pH 7.2, containing 50% glycerol
ELISA: In combination with a monoclonal capture antibody clone 59 (Cat. No.: MO-C40090B), this HRP conjugated antibody can be used as a tracer antibody in sandwich ELISA applications for human GM-CSF detection.
Store at -20°C
Horseradish peroxidase (HRP) conjugated mouse monoclonal antibody to human Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
Does not show any cross reaction with other human cytokines or growth factors tested such as M-CSF, G-CSFR, IL-8, IL-16, IL-1β, TGF-β1 and TNF-α.
GM-CSF is an extracellular homodimer polyprotein, functioning as a hematopoietic growth factor and immune modulator. It can be produced and act upon a variety of cell types, including T-lymphocytes, B-lymphocytes, monocytes/macrophages, endothelial cells, fibroblasts, stromal cells, mesothelial cells, keratinocytes, osteoblasts, uterine epithelial cells, synoviocytes, mast cells and various solid tumors. GM-CSF stimulates stem cells to produce granulocytes and monocytes to cope with infection. Recombinant GM-CSF has been applied to boost white blood cell in cancer patients after chemotherapy and may also be useful as an immune tonic for anemia and AIDS patients.