Purified recombinant human EGF, 6kDa, 53 amino acid residues
Human, other species not tested
Pro-epidermal growth factor, EGF, Epidermal growth factor, pro-EGF, proEGF
This antibody reacts with Human EGF
Protein G affinity purified
0.01M PBS, pH 7.2, containing 50% glycerol
ELISA: This HRP conjugated antibody can be used in sandwich ELISA for EGF detection. The matched antibody (capture) is clone S-134 (Anogen Cat No.: MO-C40044D).
Store at -20°C
Horseradish peroxidase (HRP) conjugated mouse monoclonal antibody to human epidermal growth factor (EGF)
Does not cross react with other human cytokines tested such as IL-1β, IL-8, MCAF and TGF-β.
Epidermal growth factor (EGF), along with its receptor EGFR, plays an important role in cell proliferation, differentiation and survival. The binding of EGF to EGFR triggers the intrinsic tyrosine kinase activity of EGFR, activates signalling molecules and stimulates the synthesis of proteins and DNAs.EGF is crucial for maintaining mucosal lining in gastrointestinal duct and for healing of oral and gastroesophageal ulcers. EGF signalling is needed for cancer growth. Monoclonal antibodies that block EGFR have been applied for lung cancer and colon inhibition.