Ship on Dry Ice
LinkLight™ U2-OS S1PR5 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human S1PR5 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
S1PR5 acts as a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. This may also regulate transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.