Tel: 800-943-6396 Fax: 888-253-6691 Email: info@bonopusbio.com

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Bon Opus Biosciences LLC 86 Summit Ave. Suite LL300B Summit NJ 07901 USA Tel: 800-943-6396 Fax: 888-253-6691

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General Information: info@bonopusbio.com Ordering: orders@bonopusbio.com

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BC050054
2 Vials
$17,000.00
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Cat No.: 
BC050054

LinkLight™ U2-OS PTH1R / β-arrestin Cell Line

Collection: 
Product Type: 
ALTnames: 
PTHR1
Packaging: 
Ship on Dry Ice
Storage: 
Liquid Nitrogen
Description: 
LinkLight™ U2-OS PTH1R / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human PTH1R pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
Background: 
PTH1R acts as a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). It is a member of the G-protein coupled receptor family 2. Activity is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis.
1061-S
Target Protein: 
PTH1R
Target Species: 
Human
Accession Number: 
Q03431
Host Cell Lines: 
U2-OS
Assay Protocol: 
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.