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LinkLight™ U2-OS P2YR12 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human P2YR12 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
P2YR12 is a member of the G-protein coupled receptor superfamily, and is involved in platelet aggregation. This family has different subtypes with unique pharmacological selectivity, for various adenosine and uridine nucleotides. P2YR12 is a potential target for the treatment of thromboembolisms and other clotting disorders.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.