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LinkLight™ U2-OS P2RY4 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human P2RY4 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
P2RY4 is a member of the G-protein coupled receptor superfamily, and acts as a receptor to uridine nucleotides, and is partially responsive to ATP, but not responsive to ADP. This family has different subtypes with unique pharmacological selectivity, for various adenosine and uridine nucleotides.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.