Ship on Dry Ice
LinkLight™ U2-OS NPSR / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human NPSR pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
NPSR acts as a G-protein coupled receptor for neuropeptide S (NPS), and promotes mobilization of intracellular Ca2+ stores, but inhibits cell growth in response to NPS binding. NPSR is also involved in pathogenesis of asthma and other IgE-mediated diseases.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.