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LinkLight™ U2-OS LPAR3 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human LPAR3 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
LPAR3 is a member of the G protein-coupled receptor family, and EDG family of proteins, and acts as a receptor that couples predominantly to G(q/11) alpha proteins. LPAR3 also acts as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.