Ship on Dry Ice
LinkLight™ U2-OS KISS1R / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human KISS1R pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
KISS1R acts as a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. KISS1R is reported to be involved in endocrine function regulation, as this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.