5HT2a, 5ht2, serotonin receptor 2a, HTR2A, 5 hydroxytrptamine receptor 2a, 5HT2
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LinkLight™ U2-OS HTR2A / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human HTR2A pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
HTR2A acts as a receptor for serotonin. Mutations correlate with schizophrenia and obsessive-compulsive disorders, and are also associated with antidepressant response. Different isoforms have been found for this gene due to variations in transcription.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.