G-protein coupled receptor 3, ACCA orphan receptor, GPR3, ACCA
Ship on Dry Ice
LinkLight™ U2-OS GPR3 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human GPR3 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
GPR3 is an orphan receptor with constitutive G(s) signaling activity that activates cyclic AMP. GPR3 has potential use in modulating brain functions, such as behavioral responses to stress, amyloid-beta peptide generation in neurons, and neurite outgrowth. May also maintain meiotic arrest in oocytes.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.