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LinkLight™ U2-OS GPBAR1 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human GPBAR1 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
GPBAR1 is a member of the G protein-coupled receptor (GPCR) superfamily, and acts as a cell surface receptor for bile acids. GPBAR1 is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.