Ship on Dry Ice
LinkLight™ U2-OS GALR1 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human GALR1 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
GALR1 is a neuropeptide that elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family, and expression is widely reported in the brain and spinal cord, as well as in the small intestine and heart.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.