Tel: 800-943-6396 Fax: 888-253-6691 Email: info@bonopusbio.com

Contact us:

Bon Opus Biosciences LLC 86 Summit Ave. Suite LL300B Summit NJ 07901 USA Tel: 800-943-6396 Fax: 888-253-6691

Emails:

General Information: info@bonopusbio.com Ordering: orders@bonopusbio.com

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BC050026
2 Vials
$17,000.00
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Cat No.: 
BC050026

LinkLight™ U2-OS EDNRB / β-arrestin Cell Line

Collection: 
Product Type: 
ALTnames: 
Etb
Packaging: 
Ship on Dry Ice
Storage: 
Liquid Nitrogen
Description: 
LinkLight™ U2-OS EDNRB / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human EDNRB pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
Background: 
EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
1030-S
Target Protein: 
EDNRB
Target Species: 
Human
Accession Number: 
P24530
Host Cell Lines: 
U2-OS
Assay Protocol: 
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.