Ship on Dry Ice
LinkLight™ U2-OS DRD5 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human DRD5 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
DRD5 acts as a receptor that stimulates adenylyl cyclase, and refers to the D5 subtype of the dopamine receptor. Expression is reported in neurons in the limbic regions of the brain. DRD5 has a 10-fold higher affinity for dopamine than DRD1. Pseudogenes related to this gene reside on chromosomes 1 and 2.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.