Ship on Dry Ice
LinkLight™ U2-OS DRD3 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human DRD3 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
DRD3 refers to the D3 subtype of the five (D1-D5) dopamine receptors. D3 activity is mediated by G proteins which inhibit adenylyl cyclase. DRD3 is located in the limbic areas of the brain, associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.