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LinkLight™ U2-OS CXCR7 ß / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human CXCR7 ß pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
CXCR7 is a member of the G-protein coupled receptor family, and also acts as a coreceptor for Human Immunodeficiency Viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.