V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1
Ship on Dry Ice
LinkLight™ U2-OS CX3CR1 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human CX3CR1 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
CX3CR1 acts as a receptor for the CX3C chemokine fractalkine, and mediates adhesive and migratory functions. CX3CR1 also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro); of which, isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.