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LinkLight™ U2-OS CHRM3 / β-arrestin Cell Line" is a stable monoclonal cell line in U2-OS cells, targeting Human CHRM3 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
CHRM3 is a member of G protein-coupled receptor superfamily. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.