M2, Muscarinic acetylcholine receptor M2, CHRM2
Ship on Dry Ice
LinkLight™ U2-OS CHRM2 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human CHRM2 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
CHRM2 is a member of G protein-coupled receptor superfamily. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.