Ship on Dry Ice
LinkLight™ U2-OS CCR6 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human CCR6 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
CCR6 is a member of the beta chemokine receptor family. Expression is preferentially done by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha), and is involved in B-lineage maturation and antigen-driven B-cell differentiation, and may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.